Preadult Parental Diet Affects Offspring Development and Metabolism in Drosophila melanogaster
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| Authors: | Luciano M Matzkin Sarah Johnson Christopher Paight Therese A Markow |
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| Institution: | 1. Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, Alabama, United States of America.; 2. Section of Cell and Developmental Biology, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America.; 3. Laboratorio Nacional de Genomica de la Biodiversidad, Centro de Investigaciones y Estudios Avancados, Irapuato, Guanajuato, Mexico.; Queen Mary University of London, United Kingdom, |
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| Abstract: | When Drosophila melanogaster larvae are reared on isocaloric diets differing in their amounts of protein relative to sugar, emerging adults exhibit significantly different development times and metabolic pools of protein, glycogen and trigylcerides. In the current study, we show that the influence of larval diet experienced during just one generation extends into the next generation, even when that subsequent generation had been shifted to a standard diet during development. Offspring of flies that were reared on high protein relative to sugar underwent metamorphosis significantly faster, had higher reproductive outputs, and different metabolic pool contents compared to the offspring of adults from low protein relative to sugar diets. In addition, isofemale lines differed in the degree to which parental effects were observed, suggesting a genetic component to the observed transgenerational influences. |
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