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In Vitro Electrochemical Corrosion and Cell Viability Studies on Nickel-Free Stainless Steel Orthopedic Implants
Authors:Erfan Salahinejad  Mohammad Jafar Hadianfard  Digby Donald Macdonald  Samin Sharifi-Asl  Masoud Mozafari  Kenneth J. Walker  Armin Tahmasbi Rad  Sundararajan V. Madihally  Lobat Tayebi
Abstract:The corrosion and cell viability behaviors of nanostructured, nickel-free stainless steel implants were studied and compared with AISI 316L. The electrochemical studies were conducted by potentiodynamic polarization and electrochemical impedance spectroscopic measurements in a simulated body fluid. Cytocompatibility was also evaluated by the adhesion behavior of adult human stem cells on the surface of the samples. According to the results, the electrochemical behavior is affected by a compromise among the specimen''s structural characteristics, comprising composition, density, and grain size. The cell viability is interpreted by considering the results of the electrochemical impedance spectroscopic experiments.
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