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Blood pressure and thermal responses to whole body cold exposure in mildly hypertensive subjects |
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| Authors: | Silja Komulainen Tarja Oja Hannu Rintam ki Hannu Virokannas Sirkka Kein nen-Kiukaanniemi |
| Affiliation: | aDepartment of Public Health Science and General Practice, University of Oulu, P.O. Box 5000, FIN-90014 Oulun yliopisto, Finland bDepartment of Biology, University of Oulu, P.O. Box 3000, FIN-90014 Oulun yliopisto, Finland cOulu Regional Institute of Occupational Health, Aapistie 1, FIN-90220 Oulu, Finland dOulu University Hospital and Oulu Health Centre, Finland |
| Abstract: | Six mildly hypertensive subjects were exposed three times to −15 °C (wind 3.5 m/s) for 15 min. After an initial exposure for familiarisation, second and third exposures were arranged in a random double blind, crossover fashion after a week's ingestion of hydrochlorothiazide or placebo. Cold decreased skin temperatures, but not rectal temperature. Blood pressure increased 30/20 mmHg and heart rate decreased 12 beats/min by cold. Blood pressure seems to react in 3 min to changes in ambient temperature. The skin temperatures of uncovered body parts were apparently responsible for that. Hydrochlorothiazide did not affect either cardiovascular or thermal responses in cold. |
| Keywords: | Whole body cold exposure Blood pressure Temperature Man Hydrochlorothiazide Diuretic |
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