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Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex
Authors:Sue Shih-Che  Cervantes Carla  Komives Elizabeth A  Dyson H Jane
Affiliation:1 Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
2 Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0378, USA
Abstract:
Keywords:NF-κB, nuclear factor κB   ANK, ankyrin repeat domain   NLS, nuclear localization signal   PEST, amino acid composition motif rich in proline (P), glutamic acid (E), serine (S), and threonine (T) residues   MS, mass spectrometry   HSQC, heteronuclear single quantum coherence   TROSY, transverse relaxation optimized spectroscopy   NOE, nuclear Overhauser enhancement   ps-ns, picosecond to nanosecond   PF, protection factor   EDTA, ethylenediaminetetraacetic acid
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