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Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex |
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| Authors: | Sue Shih-Che Cervantes Carla Komives Elizabeth A Dyson H Jane |
| Institution: | 1 Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA 2 Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0378, USA |
| Abstract: | |
| Keywords: | NF-κB nuclear factor κB ANK ankyrin repeat domain NLS nuclear localization signal PEST amino acid composition motif rich in proline (P) glutamic acid (E) serine (S) and threonine (T) residues MS mass spectrometry HSQC heteronuclear single quantum coherence TROSY transverse relaxation optimized spectroscopy NOE nuclear Overhauser enhancement ps-ns picosecond to nanosecond PF protection factor EDTA ethylenediaminetetraacetic acid |
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