Illuminating adhesion complexes in migrating cells: moving toward a bright future |
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| Authors: | Webb Donna J Brown Claire M Horwitz Alan F |
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| Affiliation: | Department of Cell Biology, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA. djw2p@virginia.edu |
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| Abstract: | Cell migration is a complex, tightly regulated process that involves the continuous formation and disassembly of adhesions. Despite the importance of these processes, very little is known about the factors that regulate adhesion dynamics during migration. Recent advances in imaging technologies are allowing monitoring of these processes during migration and are providing insight into the mechanisms that regulate them. |
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