|
|||||
|
|
Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation |
|
| Authors: | Nathalie Busso Veronique Chobaz-Péclat Justin Hamilton Pieter Spee Nicolai Wagtmann Alexander So |
| Affiliation: | (1) Laboratoire de Rhumatologie, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland;(2) Cardiovascular Research Institute, University of California at San Francisco, 94143, Parnassus Avenue, San Francisco, California, USA;(3) Australian Centre for Blood Diseases, Monash University, 3004, 89 Commercial Rd, Melbourne, Victoria, Australia;(4) Biopharmaceuticals Biology, Novo Nordisk R&D, 2760 Bagsvaerd, Denmark |
| Abstract: | IntroductionTissue factor (TF) activation of the coagulation proteases enhances inflammation in animal models of arthritis and endotoxemia, but the mechanism of this effect is not yet fully understood – in particular, whether this is primarily due to fibrin formation or through activation of protease activated receptors (PARs). |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |