Activation of the alternative pathway of complement by malassezia ovalis (Pityrosporum ovale) |
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Authors: | Patricia W Belew E W Rosenberg B R Jennings |
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Institution: | (1) Departments of Pathology and Medicine (Dermatology), University of Tennessee Center for the Health Sciences, 38163 Memphis, Tennessee, USA |
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Abstract: | Activation of C3 and factor B in normal human serum by P. ovale was demonstrated using a standard unidirectional immunoelectrophoresis technique. Activation of complement by the alternative (properdin) pathway is a possible mechanism by which P. ovale may mediate an inflammatory response. |
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