Amino acid size, charge, hydropathy indices and matrices for protein structure analysis |
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Authors: | JC Biro |
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Affiliation: | (1) Homulus Foundation, San Francisco, CA, USA |
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Abstract: | Background Prediction of protein folding and specific interactions from only the sequence (ab initio) is a major challenge in bioinformatics. It is believed that such prediction will prove possible if Anfinsen's thermodynamic principle is correct for all kinds of proteins, and all the information necessary to form a concrete 3D structure is indeed present in the sequence. |
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