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Bacterial lipopolysaccharide induces apoptosis in the trout ovary |
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| Authors: | Simon MacKenzie Nuria Montserrat Mario Mas Laura Acerete Lluis Tort Aleksei Krasnov Frederick W Goetz Josep V Planas |
| Institution: | 2. Unitat de Fisiologia Animal, Departament de Biologia Cellular, Fisiologia i d'Immunologia, Facultat de Ciencies Universitat Autonoma de Barcelona, versBellaterra, Barcelona, Spain 1. Departament de Fisiologia Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain 3. Institute of Applied Biotechnology, University of Kuopio, Kuopio, Finland 5. Akvaforsk, PO Box 5010, N-1432 ?, Norway 4. Great Lakes Water Institute, University of Wisconsin-Milwaukee, Wisconsin, USA |
| Abstract: | BackgroundIn mammals it is well known that infections can lead to alterations in reproductive function. As part of the innate immune response, a number of cytokines and other immune factors is produced during bacterial infection or after treatment with lipopolysaccharide (LPS) and acts on the reproductive system. In fish, LPS can also induce an innate immune response but little is known about the activation of the immune system by LPS on reproduction in fish. Therefore, we conducted studies to examine the in vivo and in vitro effects of lipopolysaccharide (LPS) on the reproductive function of sexually mature female trout. |
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