MathDAMP: a package for differential analysis of metabolite profiles |
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| Authors: | Richard Baran Hayataro Kochi Natsumi Saito Makoto Suematsu Tomoyoshi Soga Takaaki Nishioka Martin Robert and Masaru Tomita |
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| Institution: | (1) Institute for Advanced Biosciences, Keio University, Tsuruoka Yamagata, 997-0017, Japan;(2) Department of Biochemistry and Integrative Medical Biology, School of Medicine, Keio University, Shinanomachi, Shinjuku-ku Tokyo, 160-8582, Japan;(3) Institute of Chemistry, Slovak Academy of Sciences, D?bravsk? cesta 9, 845 38 Bratislava, Slovakia |
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| Abstract: | Background With the advent of metabolomics as a powerful tool for both functional and biomarker discovery, the identification of specific
differences between complex metabolite profiles is becoming a major challenge in the data analysis pipeline. The task remains
difficult, given the datasets' size, complexity, and common shifts in migration (elution/retention) times between samples
analyzed by hyphenated mass spectrometry methods. |
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