XRate: a fast prototyping, training and annotation tool for phylo-grammars |
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| Authors: | Peter S Klosterman Andrew V Uzilov Yuri R Bendaña Robert K Bradley Sharon Chao Carolin Kosiol Nick Goldman Ian Holmes |
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| Affiliation: | (1) Department of Bioengineering, University of California, Berkeley, CA, USA;(2) European Bioinformatics Institute, Hinxton, Cambridgeshire, UK;(3) Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY, USA |
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| Abstract: | Background Recent years have seen the emergence of genome annotation methods based on the phylo-grammar, a probabilistic model combining continuous-time Markov chains and stochastic grammars. Previously, phylo-grammars have required considerable effort to implement, limiting their adoption by computational biologists. |
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