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Cytogenetics of human sperm: meiotic segregation in two translocation carriers. |
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| Authors: | B Brandriff L Gordon L K Ashworth V Littman G Watchmaker and A V Carrano |
| Abstract: | Meiotic segregation products were studied in sperm from two men heterozygous for the reciprocal translocations t(8;15)(p22;q21) and t(3;16)(p23;q24). A total of 226 and 201 sperm complements, respectively, were analyzed. In each translocation, 63% of complements were unbalanced, and alternate and adjacent 1 percentages were similar. The 3:1 segregation frequencies produced by the two translocations were 3.5% and 5.0%. |
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