GeneSplicer: a new computational method for splice site prediction |
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Authors: | Pertea M Lin X Salzberg S L |
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Affiliation: | The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. |
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Abstract: | GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes. The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency. |
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