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Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15 |
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| Authors: | Juli E Jones Samuel M Cadena Chenguang Gong Xiaomei Wang Zhiping Chen Sharon X Wang Chad Vickers Hong Chen Estelle Lach-Trifilieff John R Hadcock David J Glass |
| Institution: | 1. Novartis Institutes for Biomedical Research, 181 Massachusetts Avenue, Cambridge, MA 02139, USA;2. Novartis Institutes for Biomedical Research, 4002 Basel, Switzerland |
| Abstract: |  |
| Keywords: | GDF11 Activin A GDF15 cachexia skeletal muscle atrophy myostatin ActRII TGFbeta |
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