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Hybridization Kinetics Explains CRISPR-Cas Off-Targeting Rules
Authors:Misha Klein  Behrouz Eslami-Mossallam  Dylan Gonzalez Arroyo  Martin Depken
Institution:1. Kavli Institute of NanoScience and Department of BioNanoScience, Delft University of Technology, Delft 2629HZ, the Netherlands
Abstract:
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  • Keywords:CRISPR  Cas9  Cpf1  RNA guided nuclease  kinetic modeling  off-target prediction  genome engineering
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