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Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing
Authors:Isabelle Stévant  Yasmine Neirijnck  Christelle Borel  Jessica Escoffier  Lee B Smith  Stylianos E Antonarakis  Emmanouil T Dermitzakis  Serge Nef
Institution:1. Department of Genetic Medicine and Development, University of Geneva, 1211 Geneva, Switzerland;2. iGE3, Institute of Genetics and Genomics of Geneva, University of Geneva, 1211 Geneva, Switzerland;3. SIB, Swiss Institute of Bioinformatics, University of Geneva, 1211 Geneva, Switzerland;4. MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh EH16 4TJ, UK;5. School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia
Abstract:
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  • Keywords:single-cell RNA-seq  sex determination  testis  Sertoli cell  fetal Leydig cell  progenitors  differentiation  lineage specification  cell-fate decision  gene expression
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