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Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene |
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| Authors: | Koen C. Oost Lisa van Voorthuijsen Arianna Fumagalli Rik G.H. Lindeboom Joep Sprangers Manja Omerzu Maria J. Rodriguez-Colman Maria C. Heinz Ingrid Verlaan-Klink Madelon M. Maurice Boudewijn M.T. Burgering Jacco van Rheenen Michiel Vermeulen Hugo J.G. Snippert |
| Affiliation: | 1. Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands;2. Oncode Institute, Utrecht, the Netherlands;3. Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, the Netherlands;4. Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands |
| Abstract: |  |
| Keywords: | organoids intestine colorectal cancer stem cells LGR5 ASCL2 |
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