Effect of DMSO on the dielectric properties of canine kidney tissue |
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Authors: | Kenneth R Foster RThomas Bell Richard Whittington Bohdan Denysyk |
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Institution: | 1. Armed Forces Radiobiology Research Institute, Bethesda, Maryland 20014, USA;2. Naval Medical Research Institute, Bethesda, Maryland 20014 USA |
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Abstract: | The dielectric permittivity and conductivity of canine kidney tissue samples were measured at Rf frequencies between ?20 °C and +20 °C. Some of the kidneys had been perfused with DMSO (10%) in canine plasma, others with physiological saline alone. The DMSO greatly increases the conductivity of frozen tissue above that of tissue not treated with this cryoprotectant. Apparently, the chief reason for nonuniform heating of a partially frozen organ in a microwave field is the great change in tissue conductivity as it thaws. We suggest that the effect on the conductivity of tissue should be considered in the choice of a cryoprotectant for tissues which are to be thawed by microwave or radiofrequency irradiation. |
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