TaqI dimorphic site in a human pancreatic phospholipase A2 (PLA2) gene localized on chromosome 12 |
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| Authors: | P M Frossard P E Newman G G Lestringant |
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| Institution: | (1) Department of Pathology, FMHS, Al Ain, UAE;(2) Department of Dermatology, Tawam Hospital, Al Ain, UAE;(3) Department of Pathology, Faculty of Medicine and Health Sciences, P.O. Box 17666, Al Ain, United Arab Emirates |
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| Abstract: | We report the identification of a TaqI dimorphic site in the first intron of a human phospholipase A2 gene that has been localized on chromosome 12. This single two-allele polymorphism was detected by DNA blot hybridization using a full-length, 584 bp human phospholipase A2 cDNA isolated from a human lung  gt10 cDNA library. Fragment lengths were detected at either 1.3 kb or 2.2 kb. The PIC value of this dimorphism was 0.369 in a random population of 353 Caucasians. |
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