| 东当归对四氯化碳及乙醇性肝损伤的保护作用 |
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| 引用本文： | 张善玉,金在久,申英爱,朴惠顺.东当归对四氯化碳及乙醇性肝损伤的保护作用[J].中国野生植物资源,2003,22(1):42-44. |
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| 作者姓名： | 张善玉 金在久 申英爱 朴惠顺 |
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| 作者单位： | 延边大学药学院,吉林,延吉,133000 |
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| 摘 要： | 研究东当归水提取物对四氯化碳及乙醇所致小鼠SGPT和SGOT活性升高的影响。在四氯化碳及乙醇所致小鼠急性肝损伤的血清中检测SGPT和SGOT值。结果表明，37．5％、75．0％和150．0％东当归水提物在体内显著抑制四氯化碳及乙醇所致小鼠SGPT值和／或SGOT值升高。东当归水提取物对小鼠四氯化碳及乙醇性肝损伤具有保护作用。
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| 关 键 词： | 东当归 四氯化碳 乙醇 肝损伤 保护作用 SGOT SGPT 水提物 |
| 修稿时间： | 2002年7月15日 |
Protection Action of the Ligusticum acutiloba for CCl4 and Alcohal induced Liver Damage |
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| Zhang Shanyu,Jin Zaijiu,Shen Yingai,Piao Huishun.Protection Action of the Ligusticum acutiloba for CCl4 and Alcohal induced Liver Damage[J].Chinese Wild Plant Resources,2003,22(1):42-44. |
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| Authors: | Zhang Shanyu Jin Zaijiu Shen Yingai Piao Huishun |
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| Abstract: | OBJETIVE: Mouse model of CCl4 and Alcohol induced acute liver damage were used to study the effects of the decoction of the Ligusticum acutiloba (Sieb. et Zucc)Kitag. for the activities of SGPT an SGOT METHODS:The activites of SGPT and SGOT from the serums in mouse of CCl 4 and alcohol induced acute liver damage were detected by chemical method. RESULTS:the 37.5% ?75.0% and 150.0% decoction of Ligusticum acutiloba (Sieb. et Zucc)Kitag. significantly reduced CCl 4 and Alcohol induced hepatocyte damage by decreasing SGPT and/or SGOT.CONCLUSION: the decoction of Ligusticum acutiloba (Sieb. et Zucc)Kitag. has protecting effects for mouse hepatocyte damage by CCl 4 and alcohol. |
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| Keywords: | Ligusticum acutiloba CCl 4: Alcohol Protecting effects for liver |
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