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A novel anticonvulsant modulates voltage‐gated sodium channel inactivation and prevents kindling‐induced seizures
Authors:Muhammad N. Ashraf  Cezar Gavrilovici  Syed U. Ali Shah  Farzana Shaheen  Muhammad I. Choudhary  Atta‐ur Rahman  Margaret Fahnestock  Shabana U. Simjee  Michael O. Poulter
Affiliation:1. H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, , Karachi, Pakistan;2. Department of Psychiatry and Behavioural Neurosciences, Faculty of Medicine, McMaster University, , Hamilton, Ontario, Canada;3. Robarts Research Institute, Department of Physiology and Pharmacology, University of Western Ontario, , London, Ontario, Canada;4. Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, , Karachi, Pakistan
Abstract:
Keywords:brain‐derived neurotrophic factor  electrophysiology  Isoxylitones [E/Z]  steady‐state inactivation
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