Binding of the repressor complex REST‐mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Binding of the repressor complex REST‐mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models

Authors:	Paola Conforti Chiara Zuccato Germano Gaudenzi Alessandro Ieraci Stefano Camnasio Noel J. Buckley Cesare Mutti Franco Cotelli Alessandro Contini Elena Cattaneo

Affiliation:	1. Department of BioSciences, Università degli Studi di Milano, , Milano, Italy;2. Center for Stem Cell Research, Università degli Studi di Milano, , Milano, Italy;3. Department of Pharmaceutical and Biomolecular Science, Università degli Studi di Milano, , Milano, Italy;4. King's College London, Institute of Psychiatry, Centre for the Cellular Basis of Behavior, , London, UK;5. Department of Pharmaceutical Science, Division of General and Organic Chemistry “A. Marchesini”, Università degli Studi di Milano, , Milano, Italy

Abstract:

Keywords:	BDNF Huntington's disease (HD) protein– protein interaction REST/NRSF virtual drug screening