1,2,4-Triazolo mercapto and aminonitriles as potent antifungal agents |
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| Authors: | Collin Xavier Sauleau Armelle Coulon Joël |
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| Institution: | Department of Pharmaceutical Chemistry, Faculty of Pharmacy, avenue du Pr Léon Bernard, F-35043 Rennes Cedex, France. xavier.collin@univ-rennes1.fr |
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| Abstract: | A series of 3-mercapto-1,2,4-triazoles mono or disubstituted at 2-, 3- or 4-positions were synthesized and evaluated as antifungal agents. Many of these derivatives exhibit high activity against Candida albicans and Candida tropicalis. |
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