Allelic profile at 37 biochemical loci of two inbred strains of the house mouse derived from wild Mus musculus musculus |
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| Authors: | O H von Deimling J Forejt T F Wienker |
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| Affiliation: | Abteilung Chemische Pathologie, Universit?t Freiburg, Federal Republic of Germany. |
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| Abstract: | Two newly established inbred strains derived from Mus musculus musculus, designated PWD/Ph (F29) and PWK/Ph (F33), were examined for their alleles at 37 biochemical loci located on 12 different chromosomes. The allelic pattern showed characteristic differences from those observed in common inbred strains. The genetic distance D between PWK/Ph and PWD/Ph was 0.027, whereas the corresponding values for the genetic distances between PWK/Ph and C57BL/6J, DBA/2J, BALB/cJ and SWR/J were 0.777, 0.721, 0.721 and 0.838 respectively. New allozymes are described as being controlled by the loci Es-23, Pre-2 and Tam-1. The genetic relationship to M.m.molossinus is indicated by identical alleles at six other loci (Es-2, Es-9, Es-10, Es-11, Es-18 and Es-22). |
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