New insights into Whipple’s disease and Tropheryma whipplei infections |
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| Authors: | Benoit Desnues Khatoun Al Moussawi Florence Fenollar |
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| Institution: | 2. Shandong Provincial Key Laboratory of Functional Macromolecular Biophysics, Dezhou University, Dezhou, Shandong Province China;3. School of Physics and Electronic Information, Dezhou University, Dezhou, Shandong Province China;4. Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana;5. School of Informatics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana;11. School of Information and Communication Technology, Griffith University, Southport, Australia;1. Service of Infectious Diseases, Department of Medical Specialties, University Hospitals Geneva, Switzerland;2. Bacteriology laboratory, Department of Laboratories and Genetic Medicine, University Hospitals Geneva, Switzerland;3. Internal Medicine Department, University Hospitals Geneva, Switzerland;4. Division of Cardiovascular Surgery, Department of Surgery, University Hospitals Geneva, Switzerland;5. Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, 13005 Marseille, France |
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| Abstract: | Whipple’s disease is a rare multi-systemic disease associated with the ubiquitous environmental bacterium Tropheryma whipplei. Over the last 10 years, since the isolation of the bacterium, recent advances in medical microbiology, epidemiology and cellular biology have provided major insights into the understanding of the pathophysiology of T. whipplei infections that may result in Whipple’s disease. |
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