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Evolution of Renal-Disease Factor APOL1 Results in Cis and Trans Orientations at the Endoplasmic Reticulum That Both Show Cytotoxic Effects
Authors:Daria Mü  ller,Jü  rgen Schmitz,Katharina Fischer,Daniel Granado,Ann-Christin Groh,Vanessa Krausel,Simona Mareike Lü  ttgenau,Till Maximilian Amelung,Hermann Pavenstä  dt,Thomas Weide
Affiliation:1. Internal Medicine D (MedD), Molecular Nephrology, University Hospital of Münster (UKM), Münster, Germany;2. Institute of Experimental Pathology, ZMBE, University of Münster, Münster, Germany
Abstract:
Keywords:APOL1   APOL2   endoplasmic reticulum   evolutionary medicine   APOL gene family   APOL phylogeny   APOL selection analyses   kidney disease
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