Terpenoids from Tripterygium wilfordii var. regelii |
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Affiliation: | 1. School of Pharmacy, Lanzhou University, Lanzhou 730000, People''s Republic of China;2. Institute of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou 730000, People''s Republic of China;3. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People''s Republic of China;1. Department of Pharmacognosy, Faculty of Pharmacy, Yeditepe University, TR-34755, Kayışdağı, İstanbul, Turkey;2. Department of Pharmacognosy, Faculty of Pharmacy, University of Szeged, Szeged 6720, Hungary;3. Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Szeged 6720, Hungary;4. Interdisciplinary Centre of Natural Products, University of Szeged, Szeged 6720, Hungary |
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Abstract: | The methanol extract of dried stem barks of Tripterygium wilfordii Hook fil. var regelii afforded two new triterpenes: 22-hydroxy-3, 19,24-trinor-D:A-friedoolenane-1(10), 5, 7-triene-2-oic acid methyl ester, named regelone, and 3-methyl-23-ol-oxotingenol; a new diterpene—8β, 19-dihydroxy-3-oxopimar- 15-ene; and three known triterpenes-3-methyl-22-β, 23-diol-6-oxotingenol, tingenin B and cangoronin. Their structures were established on the basis of chemical and spectroscopic studies. ©1997 Elsevier Science Ltd. All rights reserved |
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