Purification and characterization of a calcium binding protein with "synexin-like" activity from human blood platelets |
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| Authors: | Q Zhuang A Stracher |
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| Affiliation: | Department of Biochemistry, State University of New York Health Science Center at Brooklyn 11203. |
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| Abstract: | A calcium binding protein of Mr = 54,000 has been isolated from human blood platelets. This protein has been shown to enhance Ca2+-induced aggregation of phosphatidylserine liposomes, suggesting that it may be a member of a recently recognized class of binding proteins known to interact with phospholipids and the membrane in a Ca2+ dependent manner. Because of the "synexin-like" activity of this protein it may be involved in Ca2+ regulated platelet secretion as well as cell motility. |
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