Distribution of CCR5-delta32, CCR2-64I, and SDF1-3'A mutations in populations from the Brazilian Amazon region |
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| Authors: | De Pinho Lott Carvalhaes Fernanda Andreza Cardoso Greice Lemos Hamoy Igor Guerreiro Liu Yan Tat Guerreiro João Farias |
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| Institution: | Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Pará, 66075-900 Belém, Para, Brazil. |
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| Abstract: | The frequency distribution of the CCR5-delta32, CCR2-64I, and SDF1-3'A alleles was studied in the urban population of Belém and in Afro-Brazilians, Amerindians, and Japanese immigrants in the state of Pará, Brazil. The results suggest that Amerindians may be genetically more susceptible to HIV-1 infection and disease progression than the other human groups studied. |
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