Cutaneous Cryptococccosis Due to Cryptococcus gattii in Immunocompetent Hosts: Case Report and Review |
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Authors: | José Miguel Dora Silvia Kelbert Caroline Deutschendorf Vanessa S Cunha Valério R Aquino Rodrigo Pires dos Santos Luciano Zubaran Goldani |
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Institution: | (1) Infectious Diseases Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil;(2) Unidade de Infectologia, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos 2350, 90035-003 Porto Alegre, RS, Brazil |
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Abstract: | Cutaneous cryptococcosis caused by C. gattii, in immunocompent patients is a rare manifestation of disease, and may be one of the first manifestations of disseminated
cryptococcosis. We report a case of disseminated cryptococcosis caused by Cryptococcus gattii presenting as cutaneous lesions in an immunocompetent patient. Previously to our report, only five cases of cutaneous involvement
by Cryptococcus gattii in immunocompetent patients have been reported in the literature. Risk factors for C. gattii infection included exposure to the eucalypt reservoirs in tropical and subtropical areas. Skin involvement corresponded to
the disseminated form of cryptococcosis in the majority of patients, and commonly affected the face and neck with different
morphologies including papules, pustules, plaques, ulcers, subcutaneous masses, cellulitis or acneiform lesions. Due to the
severity of this infection and the life threatening condition that it represents, clinicians must be aware that cutaneous
involvement may be one of the first manifestations of disseminated cryptococcosis caused by C. gattii especially in patients living and coming from endemic areas. |
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Keywords: | skin cutaneous cryptococcosis C neoformans var gattii immunocompetent |
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