|
|||||
|
|
In vitro immunization of human lymphocytes with Epstein-Barr virus capsid antigen] |
|
| Authors: | V V Kulikov A V Krivonos M E Krasheninnikov O V Borisova S L Kal'nov |
| Abstract: | Conditions for in vitro immunization of human lymphocytes from adult peripheral blood, tonsils and cord blood with Epstein-Barr Virus (EBV) capsid antigens have been studied. Pokeweed mitogen and B cell growth factor from Namalva cell line were shown to induce a significant production of specific antibodies by human lymphocytes stimulated with EBV. This effect made it possible to generate primary immune response in vitro using lymphocytes from EBV seronegative donors. |
| Keywords: | |