Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi |
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Authors: | Synthesis biological activivity of juvenele hormone analogues for |
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Institution: | Synthesis,biological activivity of juvenele hormone analogues (JHA) for |
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Abstract: | Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol were synthesized and tested for their respective biological activity as growth inhibitors for Trypanosoma cruzi, and for inhibition of tritium-labelled thymidine incorporation in T. cruzi cells. The results indicated that some JHA showed important activity against the development of the cells. |
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