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Antibody Engineering and Therapeutics: December 8-12, 2013, Huntington Beach,CA
Authors:Juan Carlos Almagro  Gary L Gilliland  Felix Breden  Jamie K Scott  Devin Sok  Matthias Pauthner  Janice M Reichert  Gustavo Helguera  Raiees Andrabi  Robert Mabry  Mathieu Bléry  James E Voss  Juha Laurén  Lubna Abuqayyas  Stefan Barghorn  Eshel Ben-Jacob  James E Crowe  James S Huston  Stephen Albert Johnston  Eric Krauland  Fridtjof Lund-Johansen  Wayne A Marasco  Paul WHI Parren  Kai Y Xu
Abstract:The 24th Antibody Engineering & Therapeutics meeting brought together a broad range of participants who were updated on the latest advances in antibody research and development. Organized by IBC Life Sciences, the gathering is the annual meeting of The Antibody Society, which serves as the scientific sponsor. Preconference workshops on 3D modeling and delineation of clonal lineages were featured, and the conference included sessions on a wide variety of topics relevant to researchers, including systems biology; antibody deep sequencing and repertoires; the effects of antibody gene variation and usage on antibody response; directed evolution; knowledge-based design; antibodies in a complex environment; polyreactive antibodies and polyspecificity; the interface between antibody therapy and cellular immunity in cancer; antibodies in cardiometabolic medicine; antibody pharmacokinetics, distribution and off-target toxicity; optimizing antibody formats for immunotherapy; polyclonals, oligoclonals and bispecifics; antibody discovery platforms; and antibody-drug conjugates.
Keywords:antibody therapeutics    antibody-drug conjugate  bispecific antibodies  protein scaffolds
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