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Interaction between Brucella abortus and cellular prion protein in lipid raft microdomains
Authors:Watarai Masahisa
Institution:Department of Applied Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro-shi, 080-8555, Hokkaido, Japan. watarai@obihiro.ac.jp
Abstract:A wide variety of pathogens employ lipid raft microdomains to infect host cells. Here, we review selected aspects of interaction between Brucella abortus and cellular prion protein, one of the lipid raft-associated molecules on the plasma membrane, when bacteria infect macrophages, and discuss the correlates of proliferation in mice.
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