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Deciphering protein function during mitosis in PtK cells using RNAi |
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| Authors: | Jane?R?Stout Rania?S?Rizk Susan?L?Kline |
| Institution: | (1) Department of Biochemistry and Molecular Biology, Indiana University Medical Sciences, Bloomington, Indiana 47405, USA;(2) Department of Biology, Indiana University, Bloomington, Indiana 47405, USA;(3) Department of Anatomy and Cell Biology, Indiana University Medical Sciences, Bloomington, Indiana 47405, USA;(4) Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, CA 92093, USA |
| Abstract: | BackgroundStudying mitosis requires a system in which the dramatic movements of chromosomes and spindle microtubules can be visualized. PtK cells, due to their flat morphology and their small number of large chromosomes, allow microscopic visualizations to be readily performed. |
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