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Ultrastructural distribution of glycogen in pancreatic islets of steroid diabetic rats
Authors:R Graf  M T?lken
Abstract:In the islets of rat pancreas, steroid diabetes induced by triamcinolon-acetonid led to glycogen infiltration of B cells. Ultracytochemically, glycogen was detected within 24 hours after glucocorticoid administration using the periodic acid-silver proteinate method according to Maxwell (1978). Glycogen was primarily located in the cytoplasm of granulated B cells but could also be detected in the halo of the secretory granules of these cells. The amount of glycogen increased during the course of the 5 day experiment. The A, D, and PP cells were free of glycogen.
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