B cell and T cell lymphopenia in systemic lupus erythematosus |
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| Authors: | M A Scheinberg E S Cathcart |
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| Affiliation: | The Arthritis and Connective Tissue Disease Section, Evans Department of Clinical Research, Boston University Medical Center, and Boston University Medical Services, Boston City Hospital, Boston, Massachusetts 02118 U.S.A. |
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| Abstract: | The absolute number and proportion of B and T lymphocytes in the peripheral blood was determined in 16 active and 11 inactive patients with systemic lupus erythematosus. The total number of B and T lymphocytes was significantly reduced when compared to normals. The population of thymus-derived cells seems to be the one predominately affected. These abnormalities improve, but are not completely reversed, when patients are in remission. |
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| Keywords: | Requests for reprints should be made to Edgar S. Cathcart M.D. Boston University Medical Center 750 Harrison Ave. Boston Mass. 02118. |
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