S-acetyl phosphopantetheine: deacetyl citrate lyase S-acetyl transferase from Klebsiella aerogenes |
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Authors: | Manoranjan Singh Brigitte Böttger Carolyn Stewart George C Brooks Paul A Srere |
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Institution: | 1. Basic Biochemistry Unit, The Veterans Administration Hospital, Dallas, Texas 75216 USA;2. the Department of Biochemistry, The University of Texas Health Science Center, Dallas, Texas 75216 USA |
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Abstract: | An enzyme has been partially purified from Klebsiella aerogenes which transfers an acetyl group from S-acetyl phosphopantetheine to deacetyl citrate lyase. This converts the deacetyl citrate lyase which has no enzyme activity, to citrate lyase, the active enzyme. A variety of other acetyl thioesters including acetyl CoA did not serve as acetyl donors. |
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