Terpenoid biotransformations by Mucor species |
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| Authors: | Eliane de Oliveira Silva Niege Araçari Jacometti Cardoso Furtado Josefina Aleu Isidro González Collado |
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| Affiliation: | 1. Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas, Universidade de S?o Paulo, Avenida do Café, s/n, Ribeir?o Prêto, S?o Paulo, 14040-903, Brazil
2. Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, República Saharaui s/n, Apdo. 40, 11510, Puerto Real, Cádiz, Spain
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| Abstract: | Terpenoids are natural products of great interest due to their widespread use in agrochemicals, drugs, fragrances, flavouring and pigments. Biocatalysts are increasingly being used in the search for new derivatives with improved properties especially to obtain structurally novel leads for new drugs which are difficult to obtain using conventional organic chemical methods. This review, covering up to the end of 2012, reports on the application of Mucor species as catalysts in terpenoid biotransformation to obtain new drug targets, enhance pharmacological activity or decrease the unwanted effects of starting material. |
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