(1) Institute of General Pathology, Laboratory of Clinical Pathology, Faculty of Medicine, University of Milan, Italy;(2) Department of Experimental Pathology, Section of Immunology, Faculty of Medicine, University of Bologna, Italy
Abstract:
Background
In Down syndrome patients several metabolic abnormalities have been reported, some involving the lipid metabolism. The level of LDL in plasma is the major determinant of the risk of vascular disease. There appear to be no studies on the LDL receptor in Down syndrome patients.