(1) Institute of Signal Processing, Tampere University of Technology, P.O. Box 553, 33101 Tampere, Finland;(2) ProSanos Corporation, Harrisburg, PA 17101, USA
Abstract:
Background
Periodic phenomena are widespread in biology. The problem of finding periodicity in biological time series can be viewed as a multiple hypothesis testing of the spectral content of a given time series. The exact noise characteristics are unknown in many bioinformatics applications. Furthermore, the observed time series can exhibit other non-idealities, such as outliers, short length and distortion from the original wave form. Hence, the computational methods should preferably be robust against such anomalies in the data.