Hop1 and the meiotic DNA-damage response |
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| Authors: | Hunter Neil |
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| Affiliation: | Section of Microbiology, University of California Davis, Davis, CA 95616, USA. nhunter@ucdavis.edu |
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| Abstract: | During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis. |
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