Potential antitumoral properties of a new copper complex with santonic acid |
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Authors: | Williams Patricia A M Zinczuk Juan Barrio Daniel A Piro Oscar E Nascimento Otaciro R Etcheverry Susana B |
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Institution: | Centro de Química Inorgánica (CEQUINOR/CONICET,UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, C. Correo 962, 1900 La Plata, Argentina. |
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Abstract: | A new copper(II) complex of santonic acid Cu(2)(sant)(4)(H(2)O)(2)].2(1/2)H(2)O has been prepared and characterized by electronic, vibrational, EPR spectral studies, and stability determinations in solution. The presence of two antiferrromagnetically coupled copper centers in the solid state was detected by EPR. The dinuclear Cu(II) complex crystallizes in the tetragonal P4(3)2(1)2 space group, with a=b=14.498(3), c=64.07(1)A. Biological studies indicate that the complex displays interesting potential antitumoral actions. |
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