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Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection
Affiliation:1. Department of Medical Microbiology and Infection Prevention, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam Infection & Immunity Institute, 1105 AZ Amsterdam, the Netherlands;2. Department of Integrative, Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA;3. International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA;4. Department of Pathology, University of Texas Medical Branch, Galveston, TX 77550, USA;5. Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77550, USA;6. Institute of Virology, Philipps University Marburg, 35043 Marburg, Germany;7. School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK;8. Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA
Abstract:
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  • Keywords:antibody  Lassa virus  cryo-EM  nanoparticles  challenge study  vaccine
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