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Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies
Institution:1. Department of Microbiology and Immunology, Albert Einstein College of Medicine, The Bronx, NY 10461, USA;2. Adimab, LLC, Lebanon, NH 03766, USA;3. Laboratório de Biologia Molecular de Flavivírus, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, 21040-360 Rio de Janeiro, Brazil;4. Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA;5. Department of Pathology, The George Washington University, Washington, DC 20037, USA;6. Laboratório de Imunologia Clínica e Alergia, Faculdade de Medicina, Universidade de São Paulo, 01246-903 São Paulo, Brazil;7. Mapp Biopharmaceutical, Inc., San Diego, CA 92121, USA;8. Departamento de Moléstias Infecciosas e Parasitárias, Faculdade de Medicina, Universidade de São Paulo, 01246-903 São Paulo, Brazil;9. Adagio Therapeutics Inc., Waltham, MA 02451, USA
Abstract:
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  • Keywords:yellow fever virus  emerging virus  vaccine  17D  South America  flavivirus  glycoprotein  neutralizing antibodies  antibody response  immunological response
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