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Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function
Affiliation:1. The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China;2. Frontier Science Center for Immunology and Metabolism, Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China;3. RNA Institute, Wuhan University, Wuhan, China;4. Department of Thyroid Surgery and National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China;5. Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA;6. Department of Hematology, West China School of Medicine, Sichuan University, Chengdu, China;7. Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, China
Abstract:
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  • Keywords:N6-methyladenosine  hematopoietic stem cells  hematopoiesis  IGF2BP2
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