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Estimating mean cost using auxiliary covariates
Authors:Pan Wenqin  Zeng Donglin
Institution:1. Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina 27705, U.S.A.
email: wendy.pan@duke.edu;2. Department of Biostatistics, CB# 7420, University of North Carolina, Chapel Hill, North Carolina 27599‐7420, U.S.A.
email: dzeng@bios.unc.edu
Abstract:We study the estimation of mean medical cost when censoring is dependent and a large amount of auxiliary information is present. Under missing at random assumption, we propose semiparametric working models to obtain low-dimensional summarized scores. An estimator for the mean total cost can be derived nonparametrically conditional on the summarized scores. We show that when either the two working models for cost-survival process or the model for censoring distribution is correct, the estimator is consistent and asymptotically normal. Small-sample performance of the proposed method is evaluated via simulation studies. Finally, our approach is applied to analyze a real data set in health economics.
Keywords:Auxiliary covariates  Cost analysis  Double robust  Kernel estimation  Missing at random  Semiparametric estimation
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