1,2-Diaryl-1-ethanone and pyrazolo [4,3-c] quinoline-4-one as novel selective cyclooxygenase-2 inhibitors |
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| Authors: | Baruah Bipul Dasu Kavitha Vaitilingam Balasubramanian Vanguri Akhila Rao Casturi Seshagiri Rao Yeleswarapu Koteswar |
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| Institution: | Inflammation Research Group, Discovery Research, Dr. Reddy's Laboratories Limited, Bollaram Road, Miyapur, -500050, Hyderabad, India. |
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| Abstract: | Novel 1,2-diaryl-1-ethanone 1 and pyrazolo 4,3-c] quinoline-4-one 2, with pharmacophores different from the known COX inhibitors were identified as selective COX-2 inhibitors. The communication briefly describes SAR of both the series. |
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