A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin |
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| Authors: | Rizzi Eleonora Dallavalle Sabrina Merlini Lucio Beretta Giovanni Luca Pratesi Graziella Zunino Franco |
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| Affiliation: | Dipartimento di Scienze Molecolari Agroalimentari, Università di Milano, Via Celoria 2, I 20133 Milano, Italy. |
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| Abstract: | A new synthesis of isoaurones related to the alleged structure of isoaurostatin, via Heck intramolecular cyclization of cinnamic esters of 2-iodophenols, is reported. The cytotoxic activity of these isoaurones is lower than that of the structurally very similar 4-arylcoumarins. |
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